A factor genetic behind the 'male infertility is what emerges from a study conducted by a team of researchers at Virginia Commonwealth University School of Medicine in Richmond (Virginia, USA) and published online in Proceedings of the National Academy of Sciences, that the dysfunction of a protein involved in sperm production could help to understand the causes of infertility in men and help research to identify new therapeutic approaches for male contraception. The
sperm, the researchers said, are produced in the testes through a three step process called " spermatogenesis. E 'during the final phase, known as spermiogenesis , "which takes place the formation of the DNA in the sperm head and tail formation , processes necessary for full maturation of sperm.
In the study on mice, researchers led by Jerome Strauss, head of the Department of Medicine, showed that male mice lacking the protein MEIG1 (meiosis Expressed gene 1) were sterile due to impaired spermiogenesis. Not only that during the research scholars have also found that the protein is associated MEIG1 the amount of protein PACRG responsible for the formation of the sperm tail, which is reduced when MEIG1 is absent. "We found that MEIG1 is essential for male fertility. Moreover, our results reveal a crucial role in the collaboration MEIG1/PACRG for the proper maturation of sperm." The study, the researchers said, not only will serve to combat infertility: Besides having an impact on fertility, in fact, our findings identify a new target for the study of drugs contraceptives for men. " Date: 09/28/2009
Author: Miriam Cesta
post By www.Kriagen.it
Male Infertility Test
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